Elucidating the structure of dna

11 Mar

In an interview for PBS’ NOVA television episode titled "The Secret of Photo 51," two of her friends recalled memories of Franklin’s school days.“She was best in science, best at maths, best in everything.One of those who laid the foundations for the ultimate discovery was the late P&S biochemist Erwin Chargaff.His simple, but significant, finding on the molecule’s composition helped lead James Watson and Francis Crick to the double helix.IN SCIENTIFIC DISCOVERY, THE “ EUREKA” MOMENT OFTEN OCCURS as a result of putting together findings made by many other contributors.Such was the case with the final elucidation of the structure of DNA, a discovery celebrating its 50th anniversary in 2003.

About 30% of the approximately 12,000 genes that they tested were expressed differently between the two groups, even before infection.

Next, they infected each culture with two types of bacteria and measured how the cells responded.

Macrophages from African Americans, they found, killed the bacteria three times faster than those of European Americans.

James Watson and Francis Crick shared the Nobel Prize with Maurice Wilkins, but many people feel that much of the credit for this world-shaking achievement should rightfully go to someone who was absent from that stage, a woman named Rosalind Franklin.

Rosalind Franklin was born July 25, 1920, and grew up in a well-known Jewish family in pre-World War II London, and was known in the family for being very clever and outspoken. Paul’s Girls’ School, a private school known for rigorous academics, including physics and chemistry.